Active and Strippable PVA/Borax/NaBO₃ Hydrogel for Effective Containment and Decontamination of Chemical Warfare Agents.

ABSTRACT: Active gels present unique potential for the decontamination of chemical warfare agents (CWAs) as they strongly adhere to surfaces, thus allowing prolonged decontamination time. Herein, we present a decontamination hydrogel based on polyvinyl alcohol/borax, which contains sodium perborate (NaBO₃), as an in situ source of the active ingredient hydrogen peroxide. Developed as a binary formulation, this gel instantly forms and effectively sticks when sprayed on various matrices, including porous and vertically positioned matrices. The gel efficiently detoxified the CWAs sarin (GB), O-ethyl S-2-(diisopropylamino)ethyl methylphosphonothioate (VX), and sulfur mustard (HD) in test tubes (2 μL CWA/0.5 mL gel) to provide nontoxic products with reaction half-lives of <3, 45

SUBMITTER: Redy Keisar O 

PROVIDER: S-EPMC7931205 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature