Cu(II)-Containing Metal-Organic Framework with 1D Hexagonal Channels for Cyanosilylation Reaction and Anticancer Activity on Osteosarcoma Cells.

ABSTRACT: A novel metal-organic framework (MOF) has been produced via Cu(NO₃)₂·6H₂O reaction with 3-(1H-tetrazol-5-yl)pyridine (HL) in water, and its chemical formula is {[(Cu(L)₂(H₂O)₂](H₂O)₈) _n } (1). Due to its high density of coordinately unsaturated sites along with large one-dimensional (1D) hexagonal channels, the activated complex 1 (1a) was explored as the solvent-free heterogeneous catalyst for cyanosilylation under mind conditions. The inhibitory function of compound 1a against the survival rate of OS-732 osteosarcoma cells was evaluated via Cell Counting Kit-8 (CCK-8) detection kit. Furthermore, the Annexin V-FITC/PI detection kit and the active oxy

SUBMITTER: Luo J 

PROVIDER: S-EPMC7931417 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature