Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India.

ABSTRACT:

Background

Type 2 diabetes (T2D), a multifactorial disease influenced by host genetics and environmental factors, is the most common endocrine disease. Several studies have shown that the gut microbiota as a close-up environmental mediator influences host physiology including metabolism. The aim of the present study is to examine the compositional and functional potential of the gut microbiota across individuals from Denmark and South India with a focus on T2D. Many earlier studies have investigated the microbiome aspects of T2D, and it has also been anticipated that such microbial associations would be dependent on diet and ethnic origin. However, there has been no large scale trans-ethnic microbiome study earlier in this direction aimed at evaluating any "universal" microbiome si

SUBMITTER: Alvarez-Silva C 

PROVIDER: S-EPMC7931542 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature