Population risk factors for severe disease and mortality in COVID-19: A global systematic review and meta-analysis.

ABSTRACT:

Aim

COVID-19 clinical presentation is heterogeneous, ranging from asymptomatic to severe cases. While there are a number of early publications relating to risk factors for COVID-19 infection, low sample size and heterogeneity in study design impacted consolidation of early findings. There is a pressing need to identify the factors which predispose patients to severe cases of COVID-19. For rapid and widespread risk stratification, these factors should be easily obtainable, inexpensive, and avoid invasive clinical procedures. The aim of our study is to fill this knowledge gap by systematically mapping all the available evidence on the association of various clinical, demographic, and lifestyle variables with the risk of specific adverse outcomes in patients with COVID-19.

Methods<

SUBMITTER: Booth A 

PROVIDER: S-EPMC7932512 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature