Genetic and Environmental Influences on Semantic Verbal Fluency Across Midlife and Later Life.

ABSTRACT: Despite the relevance of semantic fluency measures to risk for dementia and psychiatric disorders, little is known about their genetic and environmental architecture in mid-to-late life. Participants represent 21,684 middle-aged and older adult twins (M = 60.84 years, SD = 11.21; Range 40-89) from six studies from three countries participating in the Interplay of Genes and Environment across Multiple Studies (IGEMS) consortium. All completed the same measure of semantic fluency (naming animals in 60 seconds). Results revealed small-to-moderate phenotypic associations with age and education, with education more strongly and positively associated with fluency performance in females than males. Heritability and environmental influences did not vary by age. Environmental variance was smaller w

SUBMITTER: Gustavson DE 

PROVIDER: S-EPMC7933104 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature