Overminus Lens Therapy for Children 3 to 10 Years of Age With Intermittent Exotropia: A Randomized Clinical Trial.

ABSTRACT:

Importance

This is the first large-scale randomized clinical trial evaluating the effectiveness and safety of overminus spectacle therapy for treatment of intermittent exotropia (IXT).

Objective

To evaluate the effectiveness of overminus spectacles to improve distance IXT control.

Design, setting, and participants

This randomized clinical trial conducted at 56 clinical sites between January 2017 and January 2019 associated with the Pediatric Eye Disease Investigator Group enrolled 386 children aged 3 to 10 years with IXT, a mean distance control score of 2 or worse, and a refractive error between 1.00 and -6.00 diopters (D). Data analysis was performed from February to December 2020.

Interventions

Participants were randomly assigned to overminus spectacle thera

SUBMITTER: Chen AM 

PROVIDER: S-EPMC7934080 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature