Design and Implementation of the Pre-Clinical DICOM Standard in Multi-Cohort Murine Studies.

ABSTRACT: The small animal imaging Digital Imaging and Communications in Medicine (DICOM) acquisition context structured report (SR) was developed to incorporate pre-clinical data in an established DICOM format for rapid queries and comparison of clinical and non-clinical datasets. Established terminologies (i.e., anesthesia, mouse model nomenclature, veterinary definitions, NCI Metathesaurus) were utilized to assist in defining terms implemented in pre-clinical imaging and new codes were added to integrate the specific small animal procedures and handling processes, such as housing, biosafety level, and pre-imaging rodent preparation. In addition to the standard DICOM fields, the small animal SR includes fields specific to small animal imaging such as tumor graft (i.e., melanoma), tissue of origin,

SUBMITTER: Kalen JD 

PROVIDER: S-EPMC7934703 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature