Serological surveillance of noroviruses in a community-based prospective cohort: a study protocol.

ABSTRACT:

Introduction

Noroviruses are the leading cause of viral acute gastroenteritis affecting all age groups. Since 2014, the previous rarely reported GII.P17-GII.17 and recombinant GII.P16-GII.2 norovirus emerged, replacing GII.4 predominant genotype, causing increased outbreaks in China and other countries. Meanwhile, GII.4/2012 Sydney strain has re-emerged as the dominant variant in many places in 2015-2018. The role of herd immunity as the driving force during these new emerging or re-emerging noroviruses is poorly defined. Serological surveillance studies on community-based prospective cohort on norovirus are highly needed.

Methods and analyses

This study will include 1000 out of 9798 participants aged 18 years and above from Caofeidian district, Tangshan city, northern China

SUBMITTER: Wang L 

PROVIDER: S-EPMC7934767 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature