Metal-free visible-light-enabled vicinal trifluoromethyl dithiolation of unactivated alkenes.

ABSTRACT: The difunctionalization of alkenes involving a trifluoromethylthio group (SCF₃) for the conversion of versatile and readily available olefins into structurally more complex molecules has been successfully studied. However, the disproportionate dithiolation of alkenes is unknown. Herein, a transition-metal-free protocol is presented for the vicinal trifluoromethylthio-thiolation of unactivated alkenes via a radical process under mild conditions with a broad substrate scope and excellent tolerance.

SUBMITTER: Li X 

PROVIDER: S-EPMC7934782 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature