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Higher Levels of Alcohol Use Are Associated With Latent Tuberculosis Infection in Adults Living With Human Immunodeficiency Virus.

ABSTRACT: We assessed associations between hazardous alcohol use and latent tuberculosis infection (LTBI) among adults living with human immunodeficiency virus (HIV) in Uganda. We compared tuberculin skin test positivity across medium, high, and very-high alcohol use levels, classified by AUDIT-C scores. In multivariable analysis, very high use was associated with LTBI (adjusted odds ratio 1.61, 95% confidence interval: 1.03-2.50).

SUBMITTER: Puryear SB 

PROVIDER: S-EPMC7935375 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Higher Levels of Alcohol Use Are Associated With Latent Tuberculosis Infection in Adults Living With Human Immunodeficiency Virus.

Puryear Sarah B SB   Fatch Robin R   Beesiga Brian B   Kekibiina Allen A   Lodi Sara S   Marson Kara K   Emenyonu Nneka I NI   Muyindike Winnie R WR   Kwarisiima Dalsone D   Hahn Judith A JA   Chamie Gabriel G  

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20210301 5

We assessed associations between hazardous alcohol use and latent tuberculosis infection (LTBI) among adults living with human immunodeficiency virus (HIV) in Uganda. We compared tuberculin skin test positivity across medium, high, and very-high alcohol use levels, classified by AUDIT-C scores. In multivariable analysis, very high use was associated with LTBI (adjusted odds ratio 1.61, 95% confidence interval: 1.03-2.50). ...[more]

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