Concept and development of an interactive tool for trial recruitment planning and management.

ABSTRACT:

Background

Predicting and monitoring recruitment in large, complex trials is essential to ensure appropriate resource management and budgeting. In a novel partnership between clinical trial investigators of the South African Medical Research Council and industrial engineers from the Stellenbosch University Health Systems Engineering and Innovation Hub, we developed a trial recruitment tool (TRT). The objective of the tool is to serve as a computerised decisions-support system to aid the planning and management phases of the trial recruitment process.

Method

The specific requirements of the TRT were determined in several workshops between the partners. A Poisson process simulation model was formulated and incorporated in the TRT to predict the recruitment duration. The assump

SUBMITTER: Spies R 

PROVIDER: S-EPMC7936448 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature