Social cognition in individuals with 22q11.2 deletion syndrome and its link with psychopathology and social outcomes: a review.

ABSTRACT:

Background

The 22q11.2 deletion syndrome (22q11DS) is a genetic syndrome that results in a highly variable profile of affected individuals of which impairments in the social domain and increased psychopathology are the most prominent. Notably, 25-30% of affected individuals eventually develop schizophrenia/psychosis, predisposing persons with the syndrome to increased risk for this disorder. Because social cognition is considered to underlie social behavior and to be related to psychopathology, this systematic review investigated social cognition in individuals with 22q11DS and examined reported links across its domains with psychopathology and social outcomes. This can provide the basis for a closer understanding of the path from risk to disorder and will inform on the specific do

SUBMITTER: Milic B 

PROVIDER: S-EPMC7936464 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature