¹⁸F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study.

ABSTRACT:

Background

Interstitial lung disease is a common complication of systemic sclerosis (SSc-ILD), and it remains difficult to accurately predict its course. Progressing ILD could be more metabolically active, suggesting that the ¹⁸F-FDG tracer could be a tool in the managing of SSc-ILD.

Methods

In our center, SSc patients and controls (non-Hodgkin lymphoma cured after first-line regimen) who had received a PET/CT were screened retrospectively. The FDG uptake (visual intensity, pattern, SUV_max) was systematically recorded in > 30 regions of interest (ROIs) linked to SSc in a blind reviewing by 2 independent nuclear medicine physicians using a standardized form.

Results

Among the 545 SSc patients followed up in our center, 36, including 22 SSc-ILDs, h

SUBMITTER: Ledoult E 

PROVIDER: S-EPMC7936499 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature