Comparison of capillary and venous blood for malaria detection using two PCR-based assays in febrile patients in Sierra Leone.

ABSTRACT:

Background

Rapid and sensitive diagnostics are critical tools for clinical case management and public health control efforts. Both capillary and venous blood are currently used for malaria detection and while diagnostic technologies may not be equally sensitive with both materials, the published data on this subject are scarce and not conclusive.

Methods

Paired clinical samples of venous and capillary blood from 141 febrile individuals in Bo, Sierra Leone, were obtained between January and May 2019 and tested for the presence of Plasmodium parasites using two multiplexed PCR assays: the FilmArray-based Global Fever Panel (GFP) and the TaqMan-based Malaria Multiplex Sample Ready (MMSR) assay.

Results

No significant differences in Plasmodium parasite detection between c

SUBMITTER: Leski TA 

PROVIDER: S-EPMC7936501 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature