X-ray microtomography-based atlas of mouse cranial development.

ABSTRACT:

Background

X-ray microtomography (μCT) has become an invaluable tool for non-destructive analysis of biological samples in the field of developmental biology. Mouse embryos are a typical model for investigation of human developmental diseases. By obtaining 3D high-resolution scans of the mouse embryo heads, we gain valuable morphological information about the structures prominent in the development of future face, brain, and sensory organs. The development of facial skeleton tracked in these μCT data provides a valuable background for further studies of congenital craniofacial diseases and normal development.

Findings

In this work, reusable tomographic data from 7 full 3D scans of mouse embryo heads are presented and made publicly available. The ages of these embryos range f

SUBMITTER: Matula J 

PROVIDER: S-EPMC7936920 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature