Long COVID hallmarks on [18F]FDG-PET/CT: a case-control study.

ABSTRACT:

Purpose

The present study hypothesised that whole-body [18F]FDG-PET/CT might provide insight into the pathophysiology of long COVID.

Methods

We prospectively enrolled 13 adult long COVID patients who complained for at least one persistent symptom for >30 days after infection recovery. A group of 26 melanoma patients with negative PET/CT matched for sex/age was used as controls (2:1 control to case ratio). Qualitative and semi-quantitative analysis of whole-body images was performed. Fisher exact and Mann-Whitney tests were applied to test differences between the two groups. Voxel-based analysis was performed to compare brain metabolism in cases and controls. Cases were further grouped according to prevalent symptoms and analysed accordingly.

Results

In 4/13 long COVID

SUBMITTER: Sollini M 

PROVIDER: S-EPMC7937050 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature