Risk and prognostic factors of breast cancer with liver metastases.

ABSTRACT:

Background

Liver metastasis is a significant adverse predictor of overall survival (OS) among breast cancer patients. The purpose of this study was to determine the risk and prognostic factors of breast cancer with liver metastases (BCLM).

Methods

Data on 311,573 breast cancer patients from the Surveillance, Epidemiology, and End Results (SEER) database and 1728 BCLM patients from Fudan University Shanghai Cancer Center (FUSCC) were included. Logistic regression was used to identify risk factors for liver metastasis. Cox proportional hazards regression model was adopted to determine independent prognostic factors in BCLM patients.

Results

Young age, invasive ductal carcinoma, higher pathological grade, and subtype of triple-negative and human epidermal growth factor r

SUBMITTER: Ji L 

PROVIDER: S-EPMC7937288 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature