Key metabolism pathways and regulatory mechanisms of high polysaccharide yielding in Hericium erinaceus.

ABSTRACT:

Background

Hericium erinaceus, a rare edible and medicine fungus, is widely used in the food and medical field. Polysaccharides from H. erinaceus are the main bioactive compound that exert high bioactive value in the medical and healthcare industries.

Results

The genome of H. erinaceus original strain HEA was reported 38.16 Mb, encoding 9780 predicted genes by single-molecule, real-time sequencing technology. The phylogenomic analysis showed that H. erinaceus had the closest evolutionary affinity with Dentipellis sp. The polysaccharide content in the fermented mycelia of mutated strains HEB and HEC, which obtained by ARTP mutagenesis in our previous study, was improved by 23.25 and 47.45%, and a new β-glucan fraction with molecular weight 1.056 × 10⁶ Da was produc

SUBMITTER: Gong M 

PROVIDER: S-EPMC7937317 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature