Atrial Fibrillation and Longitudinal Change in Cognitive Function in CKD.

ABSTRACT:

Background

Studies in the general population suggest that atrial fibrillation (AF) is an independent risk factor for decline in cognitive function, but this relationship has not been examined in adults with chronic kidney disease (CKD). We investigated the association between incident AF and changes in cognitive function over time in this population.

Methods and results

We studied a subgroup of 3254 adults participating in the Chronic Renal Insufficiency Cohort Study. Incident AF was ascertained by 12-lead electrocardiogram (ECG) obtained at a study visit and/or identification of a hospitalization with AF during follow-up. Cognitive function was assessed biennially using the Modified Mini-Mental State Exam. Linear mixed effects regression was used to evaluate the association

SUBMITTER: McCauley MD 

PROVIDER: S-EPMC7938064 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature