Effect of High-Flow Oxygen on Exercise Performance in COPD Patients. Randomized Trial.

ABSTRACT: Background: High-flow oxygen therapy (HFOT) provides oxygen-enriched, humidified, and heated air at high flow rates via nasal cannula. It could be an alternative to low-flow oxygen therapy (LFOT) which is commonly used by patients with chronic obstructive pulmonary disease (COPD) during exercise training. Research Question: We evaluated the hypothesis that HFOT improves exercise endurance in COPD patients compared to LFOT. Methods: Patients with stable COPD, FEV₁ 40-80% predicted, resting pulse oximetry (SpO₂) ≥92%, performed two constant-load cycling exercise tests to exhaustion at 75% of maximal work rate on two different days, using LFOT (3 L/min) and HFOT (60 L/min, FiO₂ 0.45) in randomized order according to a crossover design. Pri

SUBMITTER: Bitos K 

PROVIDER: S-EPMC7938234 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature