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Right ventricular myocardial deoxygenation in patients with pulmonary artery hypertension.


ABSTRACT:

Background

In pulmonary arterial hypertension (PAH), progressive right ventricular (RV) dysfunction is believed to be largely secondary to RV ischaemia. A recent pilot study has demonstrated the feasibility of Oxygen-sensitive (OS) cardiovascular magnetic resonance (CMR) to detect in-vivo RV myocardial oxygenation. The aims of the present study therefore, were to assess the prevalence of RV myocardial ischaemia and relationship with RV myocardial interstitial changes in PAH patients with non-obstructive coronaries, and corelate with functional and haemodynamic parameters.

Methods

We prospectively recruited 42 patients with right heart catheter (RHC) proven PAH and 11 healthy age matched controls. The CMR examination involved standard functional imaging, OS-CMR imaging and na

SUBMITTER: Sree Raman K 

PROVIDER: S-EPMC7938464 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature