Is the effect of Mediterranean diet on hip fracture mediated through type 2 diabetes mellitus and body mass index?

ABSTRACT:

Background

We examined whether the inverse association between adherence to a Mediterranean diet and hip fracture risk is mediated by incident type 2 diabetes mellitus (T2DM) and body mass index (BMI).

Methods

We included 50 755 men and women from the Cohort of Swedish Men and the Swedish Mammography Cohort who answered lifestyle and medical questionnaires in 1997 and 2008 (used for calculation of the Mediterranean diet score 9mMED; low, medium, high) and BMI in 1997, and incident T2DM in 1997-2008). The cumulative incidence of hip fracture from the National Patient Register (2009-14) was considered as outcome.

Results

We present conditional odds ratios (OR) 9[95% confidence interval, CI) of hip fracture for medium and high adherence to mMED, compared with low adheren

SUBMITTER: Mitchell A 

PROVIDER: S-EPMC7938512 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature