Trends in paediatric central nervous system tumour incidence by global region from 1988 to 2012.

ABSTRACT:

Background

Central nervous system (CNS) tumours comprise 20% of childhood cancers worldwide. Whether childhood CNS tumour incidence has increased over time across geographic regions remains to be explored.

Methods

We identified CNS cancers in the Cancer in Five Continents (CI5) data and estimated age standardized incidence rates (ASRs; cases/million children) and 95% confidence intervals (95% CI), male-to-female incidence rate ratios (IRR; 95% CI) and average annual percent change in incidence (AAPC; 95% CI) by geographic region for children aged 0-19 years where data were available using Poisson regression and generalized estimating equations (GEE). Cancers included: astrocytic tumours, medulloblastoma, ependymal, oligodendroglial and mixed glioma, glioma of uncertain origi

SUBMITTER: Williams LA 

PROVIDER: S-EPMC7938516 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature