Idiopathic pulmonary fibrosis and gastroesophageal reflux disease: A population-based, case-control study.

ABSTRACT:

Background

It is unknown whether gastroesophageal reflux disease (GERD) is a risk factor or consequence of idiopathic pulmonary fibrosis (IPF). This study aimed to determine whether patients with IPF were more likely to have GERD compared with age- and sex-matched controls who either had 1) interstitial lung disease (ILD) other than IPF or 2) no diagnosed lung disease (population control).

Methods

We used the medical records-linkage system of the Rochester Epidemiology Project (REP) to identify patients with IPF who resided in Olmsted County, Minnesota, from January 1, 1997, through June 30, 2017. IPF cases were each matched with patients from 2 control groups (non-IPF ILD controls and population controls). We used conditional logistic regression to model associations betwee

SUBMITTER: Baqir M 

PROVIDER: S-EPMC7938662 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature