Enteric Infections Are Common in Patients with Flares of Inflammatory Bowel Disease.

ABSTRACT:

Objectives

Few studies have examined the role of non-Clostridium difficile enteric infections in flares of inflammatory bowel disease (IBD). Our objective was to investigate enteric infection detected by multiplex PCR stool testing in patients with IBD.

Methods

We performed a cross-sectional analysis of 9403 patients who underwent 13,231 stool tests with a gastrointestinal pathogen PCR panel during a diarrheal illness from March 2015 to May 2017. Our primary outcome was the presence of an infection. Secondary outcomes included endoscopic and histologic predictors of infection, and IBD outcomes following testing.

Results

A total of 277 patients with Crohn's disease (CD), 300 patients with ulcerative colitis (UC), and 8826 patients without IBD underwent 454, 503, and 12

SUBMITTER: Axelrad JE 

PROVIDER: S-EPMC7939066 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature