Dataset Information

Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases.

ABSTRACT: Bacterial proteases and peptidases are integral to cell physiology and stability, and their necessity in Streptococcus pneumoniae is no exception. Protein cleavage and processing mechanisms within the bacterial cell serve to ensure that the cell lives and functions in its commensal habitat and can respond to new environments presenting stressful conditions. For S. pneumoniae, the human nasopharynx is its natural habitat. In the context of virulence, movement of S. pneumoniae to the lungs, blood, or other sites can instigate responses by the bacteria that result in their proteases serving dual roles of self-protein processors and virulence factors of host protein targets.

SUBMITTER: Marquart ME

PROVIDER: S-EPMC7939560 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases.

Marquart Mary E ME

Virulence 20211201 1

Bacterial proteases and peptidases are integral to cell physiology and stability, and their necessity in Streptococcus pneumoniae is no exception. Protein cleavage and processing mechanisms within the bacterial cell serve to ensure that the cell lives and functions in its commensal habitat and can respond to new environments presenting stressful conditions. For S. pneumoniae, the human nasopharynx is its natural habitat. In the context of virulence, movement of S. pneumoniae ...[more]

PMID: 33660565

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Dataset Information

Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases.

Publications

Pathogenicity and virulence of <i>Streptococcus pneumoniae</i>: Cutting to the chase on proteases.

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