The Impact of Various Culture Conditions on Human Mesenchymal Stromal Cells Metabolism.

ABSTRACT: In vitro and in vivo analyses are closely connected, and the reciprocal relationship between the two comprises a key assumption with concern to the conducting of meaningful research. The primary purpose of in vitro analysis is to provide a solid background for in vivo and clinical study purposes. The fields of cell therapy, tissue engineering, and regenerative medicine depend upon the high quality and appropriate degree of the expansion of mesenchymal stromal cells (MSCs) under low-risk and well-defined conditions. Hence, it is necessary to determine suitable alternatives to fetal bovine serum (FBS-the laboratory gold standard) that comply with all the relevant clinical requirements and that provide the appropriate quantity of high-quality cells while preserving

SUBMITTER: Tonarova P 

PROVIDER: S-EPMC7939743 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature