Association between maternal smoking during pregnancy and risk of bone fractures in offspring: a systematic review and meta-analysis.

ABSTRACT: This study aimed to investigate the effect of maternal smoking during pregnancy (MSDP) on the risk of bone fractures in the offspring through a systematic review and meta-analysis. The PubMed, Web of Science, and Scopus databases were systematically searched for relevant articles published through July 2019. According to heterogeneity, the pooled risk ratio (RR) and odds ratio (OR) and their corresponding 95% confidence interval (CI) were obtained using fixed or random effects models. The heterogeneity and quality of the included studies were assessed by the I-squared (I2 ) statistic and the Newcastle-Ottawa scale, respectively. Sensitivity analyses were performed to test the effect of MSDP misclassification on the results. The review of 842 search records yielded 5 studies including 8,746

SUBMITTER: Ayubi E 

PROVIDER: S-EPMC7940084 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature