Association Among Blood Transfusion, Postoperative Infectious Complications, and Cancer-Specific Survival in Patients with Stage II/III Gastric Cancer After Radical Gastrectomy: Emphasizing Benefit from Adjuvant Chemotherapy.

ABSTRACT:

Objectives

This study was designed to investigate the potential additive influence of perioperative blood transfusion (BTF) and postoperative infections on cancer-specific survival (CSS) in patients with stage II/III gastric cancer (GC) after radical gastrectomy.

Methods

The medical records of 2114 consecutive stage II/III GC patients who underwent curative resection and planned to receive adjuvant chemotherapy (AC) were retrospectively reviewed. The independent predictive factors for infections were identified using univariate and multivariate analyses. Cox regression analysis was used to assess any associations between BTF, infection and CSS.

Results

A total of 507 (24.0%) received perioperative BTF and 148 (7.0%) developed infections with BTF being identified as an

SUBMITTER: Xiao H 

PROVIDER: S-EPMC7940152 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature