The Predictive and Guidance Value of Signet Ring Cell Histology for Stage II/III Colon Cancer Response to Chemotherapy.

ABSTRACT:

Purpose

To evaluate the predictive and guidance value of signet-ring cell carcinoma for chemotherapy response in stage II/III colon cancer.

Methods

Eligible patients were recruited from the Surveillance, Epidemiology and End Results (SEER) database. The differences between adenocarcinoma (AD) and SRCC groups in the incidence of patients' demographic and clinical characteristics were analyzed by Pearson's chi-squared (×2) test. Survival was analyzed using the Kaplan-Meier method, and the differences were determined by the log-rank test. Some Cox regression models were built to assess hazard ratios (HRs) of different variables with 95% confidence intervals (95% CIs).

Results

In stage II AD, it was found that the receipt of chemotherapy had significantly 12.6% decreased

SUBMITTER: Jiang H 

PROVIDER: S-EPMC7940524 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature