Quantitative assessment of the diagnostic role of mucin family members in pancreatic cancer: a meta-analysis.

ABSTRACT:

Background

The use of mucins (MUC) as specific biomarkers for various malignancies has recently emerged. MUC1, MUC4, MUC5AC, and MUC16 can be detected at different stages of pancreatic cancer (PC), and can be valuable for indicating the initiation and progression of this disease. However, the diagnostic significance of the mucin family in patients with PC remains disputed. Herein, we assessed the diagnostic accuracy of mucins in PC using a meta-analysis.

Methods

We searched the PubMed, Cochrane Library, Institute for Scientific Information (ISI) Web of Science, Embase, and Chinese databases from their date of inception to June 1, 2020 to identify studies assessing the diagnostic performance of mucins in PC. The estimations of diagnostic indicators in selected studies were ex

SUBMITTER: Wang S 

PROVIDER: S-EPMC7940915 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature