Early surgical reconstruction versus rehabilitation with elective delayed reconstruction for patients with anterior cruciate ligament rupture: COMPARE randomised controlled trial.

ABSTRACT:

Objective

To assess whether a clinically relevant difference exists in patients' perceptions of symptoms, knee function, and ability to participate in sports over a period of two years after rupture of the anterior cruciate ligament (ACL) between two commonly used treatment regimens.

Design

Open labelled, multicentre, parallel randomised controlled trial (COMPARE).

Setting

Six hospitals in the Netherlands, between May 2011 and April 2016.

Participants

Patients aged 18 to 65 with an acute rupture of the ACL, recruited from six hospitals. Patients were evaluated at three, six, nine, 12, and 24 months.

Interventions

85 patients were randomised to early ACL reconstruction and 82 to rehabilitation followed by optional delayed ACL reconstruction after a three

SUBMITTER: Reijman M 

PROVIDER: S-EPMC7941216 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature