Multimodality imaging-guided local injection of eccentric magnetic microcapsules with electromagnetically controlled drug release.

ABSTRACT:

Background

In the past decade, trackable smart drug delivery systems have played important roles in the treatment of many diseases such as cancer because the drug carriers can be visualized through their distinct physical properties. However, it is still difficult to achieve precise drug delivery because such systems usually rely on a single imaging system.

Aim

This study aimed to present a novel type of multimodality imaging-guided strategy to visualize the drug carriers of eccentric magnetic microcapsule (EMM) designed for potential treatment of hepatocellular carcinoma (HCC).

Method and results

The EMMs were prepared by using a three-phase microfluidic device. The as-prepared EMMs embedded with Fe₃O₄ nanoparticles are magnetic, with high densi

SUBMITTER: Huang W 

PROVIDER: S-EPMC7941443 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature