A first insight into the genome of Prototheca wickerhamii, a major causative agent of human protothecosis.

ABSTRACT:

Background

Colourless microalgae of the Prototheca genus are the only known plants that have consistently been implicated in a range of clinically relevant opportunistic infections in both animals and humans. The Prototheca algae are emerging pathogens, whose incidence has increased importantly over the past two decades. Prototheca wickerhamii is a major human pathogen, responsible for at least 115 cases worldwide. Although the algae are receiving more attention nowadays, there is still a substantial knowledge gap regarding their biology, and pathogenicity in particular. Here we report, for the first time, the complete nuclear genome, organelle genomes, and transcriptome of the P. wickerhamii type strain ATCC 16529.

Results

The assembled genome size was of 16.7 Mbp, making i

SUBMITTER: Bakula Z 

PROVIDER: S-EPMC7941945 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature