Novel metabolomic method to assess the effect-based removal efficiency of advanced wastewater treatment techniques.
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ABSTRACT: Unprecedented levels of chemicals of anthropogenic origin are currently released into surface waters globally. Wastewater treatment plant effluent has been identified as a major source, containing a broad mixture of pharmaceuticals and consumer chemicals. Therefore, there is a need for implementation of advanced wastewater treatment techniques, such as ozonation and adsorption methods, to reduce the contamination. However, there are conflicting findings on the toxicity of treated effluent and only limited possibilities for assessing the effect-based removal efficiency (EBRE) of different treatment techniques. Here, we describe a metabolomics approach to detect perturbations in fatty acid catabolic pathways as a proxy for biological effects. Metabolites in three fatty acid pathways were ana
SUBMITTER: Spath J
PROVIDER: S-EPMC7943040 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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