High Serum Asprosin Levels Are Associated with Presence of Metabolic Syndrome.

ABSTRACT:

Objective

Asprosin, a new adipocytokine, has reportedly been associated with glucose release, dyslipidemia, and insulin resistance (IR). However, the relationship of asprosin with metabolic syndrome (MetS) remains unknown. This study aimed to investigate serum asprosin levels in MetS as well as their association with various metabolic parameters in humans.

Methods

A total of 131 consecutive patients with MetS, and 162 age-matched, healthy subjects were recruited for this study. Serum asprosin concentrations were determined using the enzyme-linked immunosorbent assay. Lipid profile, glucose, insulin, and inflammatory markers were also measured.

Results

Serum asprosin levels were higher in subjects with MetS (23.52 [16.70, 32.05] ng/mL) than in controls (16.70 [12.87, 2

SUBMITTER: Hong T 

PROVIDER: S-EPMC7943292 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature