Etiology-specific variation in survival following non-traumatic spinal cord injury: a causal inference approach using data from a population-based cohort.

ABSTRACT:

Study design

Observational, population-based cohort study.

Objectives

To evaluate the origin and contribution to excess of survival differences following non-traumatic spinal cord injury (NTSCI) using etiology as proxy for variation in underlying health condition.

Setting

Specialized rehabilitation centers in Switzerland.

Methods

Medical record data collected by the Swiss Spinal Cord Injury cohort (SwiSCI) study were linked with mortality information from the Swiss National Cohort. Considering contemporary theory and empirical evidence, a directed acyclic graph (DAG) was developed to formally evaluate causal differences among NTSCI etiologies, relative to traumatic SCI (TSCI). Statistical inference was contingent on hazard ratios (HRs) and marginal survival dif

SUBMITTER: Buzzell A 

PROVIDER: S-EPMC7943420 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature