CoExp: A Web Tool for the Exploitation of Co-expression Networks.

ABSTRACT: Gene co-expression networks are a powerful type of analysis to construct gene groupings based on transcriptomic profiling. Co-expression networks make it possible to discover modules of genes whose mRNA levels are highly correlated across samples. Subsequent annotation of modules often reveals biological functions and/or evidence of cellular specificity for cell types implicated in the tissue being studied. There are multiple ways to perform such analyses with weighted gene co-expression network analysis (WGCNA) amongst one of the most widely used R packages. While managing a few network models can be done manually, it is often more advantageous to study a wider set of models derived from multiple independently generated transcriptomic data sets (e.g., multiple networks built from many tra

SUBMITTER: Garcia-Ruiz S 

PROVIDER: S-EPMC7943635 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature