Appropriate and Potentially Inappropriate Medication Use in Decompensated Cirrhosis.

ABSTRACT:

Background and aims

Patients with decompensated cirrhosis are prescribed numerous medications. Data are limited as to whether patients are receiving medications they need and avoiding those they do not. We examined a large national claims database (2010-2015) to characterize the complete medication profile as well as the factors associated with appropriate and potentially inappropriate medication use in 12,621 patients with decompensated cirrhosis.

Approach and results

Clinical guidelines and existing literature were used to determine appropriate and potentially inappropriate medications in decompensated cirrhosis. The total medication days' supply was calculated from pharmacy data and divided by the follow-up period for each decompensation. Ascites was the most common (86.5

SUBMITTER: Thomson MJ 

PROVIDER: S-EPMC7943648 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature