Intensity modulated radiotherapy for anal canal squamous cell carcinoma: A 16-year single institution experience.

ABSTRACT:

Introduction

To report long-term efficacy and adverse events (AEs) associated with intensity modulated radiotherapy (IMRT) for patients with anal canal squamous cell carcinoma (ASCC).

Materials and methods

This was a retrospective review of patients with ASCC who received curative-intent IMRT and concurrent chemotherapy (98%) between 2003 and 2019. Overall survival (OS), colostomy-free survival (CFS), and progression-free survival (PFS) were estimated using the Kaplan-Meier method. The cumulative incidence of local recurrence (LR), locoregional recurrence (LRR), and distant metastasis (DM) were reported. Acute and late AEs were recorded per National Cancer Institute Common Terminology Criteria for AEs.

Results

127 patients were included. The median patient age was 63 

SUBMITTER: Jethwa KR 

PROVIDER: S-EPMC7943964 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature