Bone metabolic biomarker-based diagnosis of type 2 diabetes osteoporosis by support vector machine.

ABSTRACT:

Background

Diabetes has significant effects on bone metabolism. Both type 1 and type 2 diabetes can cause osteoporotic fracture. However, it remains challenging to diagnose osteoporosis in type 2 diabetes by bone mineral density which lacks regular changes. Seen another way, osteoporosis can be ascribed to the imbalance of bone metabolism, which is closely related to diabetes as well.

Methods

Here, to assist clinicians in diagnosing osteoporosis in type 2 diabetes, an efficient and simple SVM (support vector machine) model was established based on different combinations of biochemical indexes, which were collected from patients who did the test of bone turn-over markers (BTMs) from January 2016 to March 2018 in the department of endocrine, Zhongda Hospital affiliated to Sout

SUBMITTER: Wang C 

PROVIDER: S-EPMC7944260 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature