Development and validation of a novel nomogram to predict cancer-specific survival in patients with uterine cervical adenocarcinoma.

ABSTRACT:

Background

The treatment strategies and prognostic factors for uterine cervical adenocarcinoma (UAC) primarily refer to that for squamous cell carcinoma (SCC). However, the biological behavior, treatment outcomes of UAC differ from that of SCC. This study aimed to develop and validate a prognostic nomogram for predicting the probability of 3- and 5-year cancer-specific survival (CSS) in patients with UAC.

Methods

A total of 8,991 UAC patients from the Surveillance, Epidemiology, and End Results (SEER) database were included in this study. Patients diagnosed between 1988 and 2010 (n=5,655) were enrolled for model development and internal validation, and those diagnosed between 2011 and 2016 (n=3,336) were used for temporal validation. The least absolute shrinkage and selectio

SUBMITTER: Ni X 

PROVIDER: S-EPMC7944266 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature