Heart rate fluctuation predicts mortality in critically ill patients in the intensive care unit: a retrospective cohort study.

ABSTRACT:

Background

To evaluate the association between heart rate (HR) fluctuation and mortality in critically ill patients in the intensive care unit (ICU).

Methods

A total of 27,814 patients were enrolled from the Medical Information Mart for Intensive Care database and were divided into 3 groups: low HR fluctuation [<25 beats per minute (bpm)], control (25-34 bpm), and high HR fluctuation (≥35 bpm), based on the initial 24-hour HR fluctuation (calculated as the maximum HR minus minimum HR). Multivariate Cox regression and restricted cubic spline models were used.

Results

Compared to the control group, higher risk of 28-day and 1-year mortality remained significant in an adjusted model, with hazard ratios of 1.210 [95% confidence interval (CI), 1.103-1.327] and 1.150 (95% C

SUBMITTER: Guo Q 

PROVIDER: S-EPMC7944303 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature