Accurate nomograms with excellent clinical value for locally advanced rectal cancer.

ABSTRACT:

Background

Rectal cancer accounts for approximately 30-50% of colorectal cancer. Despite its widespread use and convenience, the American Joint Committee on Cancer (AJCC) staging system for predicting survival is prone to inaccuracy, even including a survival paradox for locally advanced rectal cancer (LARC). An accurate risk stratification of LARC is essential for proper treatment selection and prognostic evaluation. Therefore, we aimed to create prognostic nomograms for LARC capable of assessing overall survival (OS) and cancer-specific survival (CSS) precisely and intuitively.

Methods

The Surveillance, Epidemiology, and End Results (SEER) database was accessed. All of the significant variables in the multivariate analysis were integrated to build the nomograms.

Results

SUBMITTER: Li Y 

PROVIDER: S-EPMC7944304 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature