Primary tumor immune score fails to predict the prognosis of colorectal cancer liver metastases after hepatectomy in Chinese populations.

ABSTRACT:

Background

Increasing evidence suggests that the immune score is significantly associated with cancer prognosis. However, the prognostic role of primary tumor immune score in colorectal cancer liver metastases (CRLM) after hepatectomy in Chinese patients has not been reported. The present study is designed to investigate whether the immune score of primary tumor can predict the postoperative survival of liver metastases in Chinese patients.

Methods

A total of 131 patients diagnosed with CRLM were included, and the corresponding primary tumor and liver metastasis specimens were acquired. An immune score ranging from 0 to 4 was established based on the counts and densities of CD3⁺ and CD8⁺ T cells in the core tumor (CT) and the invasive margin (IM). Relap

SUBMITTER: Lin HC 

PROVIDER: S-EPMC7944305 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature