Nomogram prediction for the overall survival and cancer-specific survival of patients diagnosed with Merkel cell carcinoma.

ABSTRACT:

Background

Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine carcinoma of the skin, with a high recurrence rate and a high mortality rate worldwide. The purpose of this article is to construct a nomogram that incorporates significant clinical parameters and predicts the survival of individuals with MCC.

Methods

The Surveillance, Epidemiology, and End Results (SEER) database was employed to retrospectively analyze all confirmed MCC cases from 2004 to 2015. The data was collected from 3,688 patients, and was randomized as the training or validation group (1:1 ratio). The independent factors which predicted the cancer-specific survival (CSS) and overall survival (OS) for MCC cases were searched for nomogram construction respectively. Independent parameters tha

SUBMITTER: Yin X 

PROVIDER: S-EPMC7944317 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature