Prevalence of Central Nervous System-Active Polypharmacy Among Older Adults With Dementia in the US.

ABSTRACT:

Importance

Community-dwelling older adults with dementia have a high prevalence of psychotropic and opioid use. In these patients, central nervous system (CNS)-active polypharmacy may increase the risk for impaired cognition, fall-related injury, and death.

Objective

To determine the extent of CNS-active polypharmacy among community-dwelling older adults with dementia in the US.

Design, setting, and participants

Cross-sectional analysis of all community-dwelling older adults with dementia (identified by International Classification of Diseases, Ninth Revision, Clinical Modification or International Statistical Classification of Diseases and Related Health Problems, Tenth Revision diagnosis codes; N = 1 159 968) and traditional Medicare coverage from 2015 to 2017. Medi

SUBMITTER: Maust DT 

PROVIDER: S-EPMC7944381 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature