Cost-effectiveness of a reactive oral cholera immunization campaign using Shanchol™ in Malawi.

ABSTRACT:

Background

Oral cholera vaccines (OCV) have been recommended as additional measures for the prevention of cholera. However, little is known about the cost-effectiveness of OCV use in sub-Saharan Africa, particularly in reactive outbreak contexts. This study aimed to investigate the cost-effectiveness of the use of OCV Shanchol in response to a cholera outbreak in the Lake Chilwa area, Malawi.

Methods

The Excel-based Vaccine Introduction Cost-Effectiveness model was used to assess the cost-effectiveness ratios with and without indirect protection. Model input parameters were obtained from cost evaluations and epidemiological studies conducted in Malawi and published literature. One-way sensitivity and threshold analyses of cost-effectiveness ratios were performed.

Results<

SUBMITTER: Ilboudo PG 

PROVIDER: S-EPMC7945304 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature