Growth in ataxia telangiectasia.

ABSTRACT:

Background

Ataxia telangiectasia (A-T) is a DNA repair disorder that affects multiple body systems. Neurological problems and immunodeficiency are two important features of this disease. At this time, two main severity groups are defined in A-T: classic (the more severe form) and mild. Poor growth is a common problem in classic A-T. An objective of this study was to develop growth references for classic A-T. Another objective was to compare growth patterns in classic A-T and mild A-T with each other and with the general population, using the CDC growth references. A final objective was to examine the effects of chronic infection on height.

Results

We found that classic A-T patients were smaller overall, and suffered from height and weight faltering that continued throughout

SUBMITTER: Natale VAI 

PROVIDER: S-EPMC7945359 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature