Evaluation of capillary density in psoriasis: An intrapatient study and literature review.

ABSTRACT:

Background

Dilated and tortuous vessels within elongated dermal papillae represent a histopathological clue of psoriasis. However, the number of dilated capillaries (capillary density) in psoriasis remains undefined as the results from the available studies differ significantly.

Objectives

To evaluate the capillary density in psoriasis using dermoscopy and horizontal histopathological sections (HHS), two techniques that share the horizontal view of the skin, and to compare the results with the existing data.

Methods

Twenty adult patients with stable plaque psoriasis were enrolled and, in each patient, a target area of the examined plaque, previously engraved by gently rotating a 5-mm biopsy punch device, underwent dermoscopy and biopsy for HHS. In all examined fields,

SUBMITTER: Micali G 

PROVIDER: S-EPMC7946227 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature